A concise flow synthesis of indole-3-carboxylic ester and its derivatisation to an auxin mimic

A concise flow synthesis of indole-3-carboxylic ester and its derivatisation to an auxin mimic

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An assembled suite of flow-based transformations have been used to rapidly scale-up the Casting - Cast and Splint Bandages and Tapes production of a novel auxin mimic-based herbicide which was required for preliminary field trials.The overall synthetic approach and optimisation studies are Baby Wrap described along with a full description of the final reactor configurations employed for the synthesis as well as the downstream processing of the reaction streams.